CLINICAL NOTES ON DIGITOXIN.

Notes on Clinical Method

Clinical Notes on Cancer

irrefragable pathological proof in its support. If it is inflammatory oedema, then it is not enlargement of the head and neck of the humerus ; and if it is bony enlargement, then it is cancerous and will not disappear after operation. But hear what he says in the next sentence:?"It would seem to be the first manifestations of that implication of the osseous system which becomes so painfully evi...

Accidental digitoxin intoxication: an interplay between laboratory and clinical medicine

INTRODUCTION Two Italian adults arrived at the Emergency Department referring diarrhea, nausea and vomiting for 4 days; weakness, fatigue and visual hallucinations were also complained of. Patients reported the ingestion of some leaves of a plant, which they supposed to be "donkey ears", a week before. Physical examination showed hypotension and bradycardia and ECG examination disclosed sinus r...

Clinical application of serum digitoxin levels. A simplified plasma determination.

a serum phosphorus if ATPase enzyme is available. Maintenance plasma levels range between 10 and 40 m,ug/ml with a mean value of 25 mrjug/ml. There is overlapping of maintenance and toxic serum levels in the higher ranges. Values over 45 m,ug/ml warrant careful evaluation for digitalis intoxication. Maintenance plasma levels can be achieved with or without the usual digitalizing dosage if time ...

Digitoxin—A Critical Review *

Within recent years, there has been an increasing interest in purified digitalis preparations. However, in spite of the original optimistic reports , the recent literature tends to discredit the value of the new preparations. Most criticisms fall into two groups: (A) Inadequacy of digitali-zation with the original recommended dosage schedules. (B) Increase in the incidence of drug toxicity. It ...